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CD140b (PDGFRB) Monoclonal Antibody (APB5), Functional Grade, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
28910.00 NOK - 150400.00 NOK
Specifications
| Antigen | CD140b (PDGFRB) |
|---|---|
| Clone | APB5 |
| Concentration | 1 mg/mL |
| Applications | Flow Cytometry, Functional Assay, Neutralization |
| Classification | Monoclonal |
Description
The APB5 MAb reacts with the mouse CD140b molecule, the beta chain of the platelet derived growth factor receptor (PDGF receptor). PDGFRb is a receptor tyrosine kinase that forms dimers on the surface upon ligand binding and phosphorylates substrates. Dimers of PDGFR consist of either homodimers of alpha/alpha, beta/beta, or heterodimers of alpha/beta and serve as a substrate for its kinase activity. CD140b is expressed by embryonic tissues and mesenchymal-derived cells of the adult mouse tissues. The PDGFR beta chain is reported to play a significant role in formation of fibrous atherosclerotic lesions.
CD140b (PDGFRB) Monoclonal antibody specifically detects CD140b (PDGFRB) in Mouse samples. It is validated for Flow Cytometry, Functional Assay, NeutralizationSpecifications
| CD140b (PDGFRB) | |
| 1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with no preservative; pH 7.2 | |
| AI528809; beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; CD140B; CD140b antigen; IBGC4; IMF1; JTK12; KOGS; PDGF beta chain; PDGF Receptor beta; PDGFR; Pdgfr1; PDGFR-1; PDGFRB; PDGF-R-beta; PDGFR-beta; PENTT; platelet derived growth factor receptor beta; platelet derived growth factor receptor, beta polypeptide; platelet-derived growth factor receptor 1; Platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; Platelet-derived growth factor receptor, beta; platelet-derived growth factor receptor, beta polypeptide | |
| IgG2a κ | |
| Affinity chromatography | |
| Antibody |
| APB5 | |
| Flow Cytometry, Functional Assay, Neutralization | |
| Functional Grade | |
| Rat | |
| Mouse | |
| P05622 | |
| 18596 | |
| Primary | |
| 4° C | |
| Pdgfrb |
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