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  7. 17191142

CD140b (PDGFRB) Monoclonal Antibody (APB5), Functional Grade, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-1402-38

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Product Code. 17191142

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Description

Description

The APB5 MAb reacts with the mouse CD140b molecule, the beta chain of the platelet derived growth factor receptor (PDGF receptor). PDGFRb is a receptor tyrosine kinase that forms dimers on the surface upon ligand binding and phosphorylates substrates. Dimers of PDGFR consist of either homodimers of alpha/alpha, beta/beta, or heterodimers of alpha/beta and serve as a substrate for its kinase activity. CD140b is expressed by embryonic tissues and mesenchymal-derived cells of the adult mouse tissues. The PDGFR beta chain is reported to play a significant role in formation of fibrous atherosclerotic lesions.

CD140b (PDGFRB) Monoclonal antibody specifically detects CD140b (PDGFRB) in Mouse samples. It is validated for Flow Cytometry, Functional Assay, Neutralization
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD140b (PDGFRB)
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
P05622
Rat
5 mg
Primary
Mouse
Antibody
IgG2a κ
Flow Cytometry, Functional Assay, Neutralization
APB5
Functional Grade
Pdgfrb
AI528809; beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; CD140B; CD140b antigen; IBGC4; IMF1; JTK12; KOGS; PDGF beta chain; PDGF Receptor beta; PDGFR; Pdgfr1; PDGFR-1; PDGFRB; PDGF-R-beta; PDGFR-beta; PENTT; platelet derived growth factor receptor beta; platelet derived growth factor receptor, beta polypeptide; platelet-derived growth factor receptor 1; Platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; Platelet-derived growth factor receptor, beta; platelet-derived growth factor receptor, beta polypeptide
Affinity chromatography
RUO
18596
4° C
Liquid
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