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CD11b Monoclonal Antibody (M1/70), Functional Grade, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
30070.00 NOK - 150400.00 NOK
Specifications
| Antigen | CD11b |
|---|---|
| Clone | M1/70 |
| Concentration | 1 mg/mL |
| Applications | Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Neutralization |
| Classification | Monoclonal |
Description
The M1/70 MAb reacts with mouse CD11b, the 165-170 kDa integrin alphaM. CD11b non-covalently associates with CD18 to form alphaMbeta2 integrin (Mac-1) and binds to CD54 (ICAM-1), C3bi, and fibrinogen. Mac-1 is expressed by macrophages, NK cells, granulocytes, activated lymphocytes and mouse B-1 cells in the peritoneal cavity. M1/70 is also cross-reactive to human CD11b, and can be used for the detection of this antigen on human peripheral blood monocytes, granulocytes, and a subset of NK cells. Through interactions with its ligands, CD11b participates in adhesive cell interactions.
CD11b Monoclonal antibody specifically detects CD11b in Mouse samples. It is validated for Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), NeutralizationSpecifications
| CD11b | |
| 1 mg/mL | |
| Monoclonal | |
| Liquid | |
| RUO | |
| PBS with no preservative; pH 7.2 | |
| antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); Itgam; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product | |
| IgG2b κ | |
| Affinity chromatography | |
| Antibody |
| M1/70 | |
| Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Neutralization | |
| Functional Grade | |
| Rat | |
| Mouse | |
| P05555 | |
| 16409 | |
| Primary | |
| 4° C | |
| ITGAM |
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