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  6. CD11b Monoclonal Antibody (M1/70), Functional Grade, eBioscience™, Invitrogen™

CD11b Monoclonal Antibody (M1/70), Functional Grade, eBioscience™, Invitrogen™

Product Code. 17100922
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50mg
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Product Code. Quantity unitSize
17100922 5 mg 5mg
17180912 25 mg 25mg
17190912 50 mg 50mg
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Product Code. 17100922

Brand: Invitrogen 16011238

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Descripción

Rat Monoclonal Antibody

The M1/70 MAb reacts with mouse CD11b, the 165-170 kDa integrin alphaM. CD11b non-covalently associates with CD18 to form alphaMbeta2 integrin (Mac-1) and binds to CD54 (ICAM-1), C3bi, and fibrinogen. Mac-1 is expressed by macrophages, NK cells, granulocytes, activated lymphocytes and mouse B-1 cells in the peritoneal cavity. M1/70 is also cross-reactive to human CD11b, and can be used for the detection of this antigen on human peripheral blood monocytes, granulocytes, and a subset of NK cells. Through interactions with its ligands, CD11b participates in adhesive cell interactions.

CD11b Monoclonal antibody specifically detects CD11b in Mouse samples. It is validated for Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Neutralization
TRUSTED_SUSTAINABILITY

Especificaciones

Antigen CD11b
Applications Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Neutralization
Classification Monoclonal
Clone M1/70
Concentration 1 mg/mL
Conjugate Functional Grade
Formulation PBS with no preservative; pH 7.2
Gene ITGAM
Gene Accession No. P05555
Gene Alias antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); Itgam; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product
Host Species Rat
Purification Method Affinity chromatography
Quantity 5 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16409
Target Species Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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