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CaMKIV Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 13263-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16891384

  • 3468.15 NOK / 150µL
Estimated Shipment: 22-12-2022
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Description

Description

CaM kinase IV (CaMKIV), in a calcium and calmodulin dependent manner, is implicated in phosphorylating numerous transcription factors including the CCAAT enhancer binding protein (C/EBP), serum response factor (SRF), and cyclic AMP response element binding protein (CBP). The nuclear localization of this protein is consistent with its role in mediating calcium-dependent gene expression. CaMKIV is particularly abundant in testis, T-cells, and neurons but is also found in other tissues to varying degrees. In neurons, CaMKIV is thought to play an important role in synaptic plasticity via its gene regulatory effects. In T-cells, this protein plays an important role in calcium signaling which could affect the transcription regulatory protein, nuclear factor of activated T-cells (NFAT). CaMKIV is encoded, along with calspermin, by the CaMKIV gene. It has been found that, in testes, CaMKIV is expressed in germ cells and found to be associated with chromatin. The association of CaMKIV with chromatin suggests a potential role in chromatin remodeling during nuclear condensation in spermatids.
Specifications

Specifications

CaMKIV
Polyclonal
Unconjugated
CAMK4
CaM kinase GR, CaMK GR, CAMK4, CaMKIV
Rabbit
Antigen Affinity Chromatography
RUO
12326, 25050, 814
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.3 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P08414, P13234, Q16566
CAMK4
CaMKIV Fusion Protein Ag3922
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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