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CaMKIV Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1611.84 NOK - 4593.76 NOK
Specifications
Antigen | CaMKIV |
---|---|
Concentration | 0.3 mg/mL |
Applications | Immunohistochemistry (Paraffin), Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16801394
|
Proteintech
13263-1-AP-20UL |
20 μL |
1611.84 NOK
20µL |
Estimated Shipment: 14-05-2024 Log in to see stock. |
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16891384
|
Proteintech
13263-1-AP-150UL |
150 μL |
4593.76 NOK
150µL |
Estimated Shipment: 14-05-2024 Log in to see stock. |
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Description
CaM kinase IV (CaMKIV), in a calcium and calmodulin dependent manner, is implicated in phosphorylating numerous transcription factors including the CCAAT enhancer binding protein (C/EBP), serum response factor (SRF), and cyclic AMP response element binding protein (CBP). The nuclear localization of this protein is consistent with its role in mediating calcium-dependent gene expression. CaMKIV is particularly abundant in testis, T-cells, and neurons but is also found in other tissues to varying degrees. In neurons, CaMKIV is thought to play an important role in synaptic plasticity via its gene regulatory effects. In T-cells, this protein plays an important role in calcium signaling which could affect the transcription regulatory protein, nuclear factor of activated T-cells (NFAT). CaMKIV is encoded, along with calspermin, by the CaMKIV gene. It has been found that, in testes, CaMKIV is expressed in germ cells and found to be associated with chromatin. The association of CaMKIV with chromatin suggests a potential role in chromatin remodeling during nuclear condensation in spermatids.Specifications
CaMKIV | |
Immunohistochemistry (Paraffin), Western Blot | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
P08414, P13234, Q16566 | |
12326, 25050, 814 | |
CaMKIV Fusion Protein Ag3922 | |
Primary | |
-20°C | |
CAMK4 |
0.3 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
CaM kinase GR, CaMK GR, CAMK4, CaMKIV | |
CAMK4 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |