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Thermo Scientific Chemicals 2'-Deoxyguanosine monohydrate, 98+%

Catalog No. 15443449
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Catalog No. 15443449 Lieferant Thermo Scientific Chemicals Lieferanten-Nr. J60741.06
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Beschreibung

CAS: 961-07-9 | C10H13N5O4 | 267.25 g/mol

Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.

Solubility
Soluble in NH4OH 1 M: 50 mg/mL, clear to very faintly turbid.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemische Identifikatoren

CAS 961-07-9
Molecular Formula C10H13N5O4
Molecular Weight (g/mol) 267.25
MDL Number MFCD00150760
InChI Key YKBGVTZYEHREMT-DWFKHXNSNA-N
Synonym 2'-deoxyguanosine, deoxyguanosine, guanine deoxyriboside, 2-deoxyguanosine, guanosine, 2'-deoxy, guanine deoxy nucleoside, 2'-deoxy-guanosine, 2;-deoxyguanosine, unii-g9481n71ro, guanine, 9-2-deoxy-beta-d-erythro-pentofuranosyl
PubChem CID 187790
ChEBI CHEBI:17172
IUPAC Name 2-amino-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
SMILES NC1=NC2=C(N=CN2[C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)N1

Spezifikation

Color White
Quantity 5 g
Solubility Information Soluble in NH4OH 1 M: 50mg/mL,clear to very faintly turbid.
Formula Weight 285.26 (267.25 Anhydrous)
Physical Form Crystalline Powder
Chemical Name or Material 2'-Deoxyguanosine

RUO – Research Use Only

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