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  7. 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane, 97%

1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane, 97%

Product Code. 11327616
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Product Code. 11327616 Supplier Thermo Scientific Alfa Aesar Supplier No. L11171.14
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Description

CAS: 69304-37-6 | C12H28Cl2OSi2 | 315.425 g/mol

1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane is a silylating reagent used for simultaneous protection of 3'- and 5'-hydroxy functions of ribonucleosides. It is used in the analysis of Watson-Crick and Hoogstein base pairing in nucleotides. It is also employed in the formation of ribavirin chemical delivery systems. Further, it serves as a protecting group reagent for open-chain polyhydroxy compounds. In addition to this, it is involved in the preparation of cyclic bridged peptides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane is a silylating reagent used for simultaneous protection of 3′- and 5′-hydroxy functions of ribonucleosides. It is used in the analysis of Watson-Crick and Hoogstein base pairing in nucleotides. It is also employed in the formation of ribavirin chemical delivery systems. Further, it serves as a protecting group reagent for open-chain polyhydroxy compounds. In addition to this, it is involved in the preparation of cyclic bridged peptides.

Solubility
Miscible with dimethylformamide, hexane, ethyl acetate, chloroform and dichloromethane.

Notes
Incompatible with strong oxidizing agents and water.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 69304-37-6
Molecular Formula C12H28Cl2OSi2
Molecular Weight (g/mol) 315.425
MDL Number MFCD00009655
InChI Key DDYAZDRFUVZBMM-UHFFFAOYSA-N
Synonym 1,3-dichloro-1,1,3,3-tetraisopropyldisiloxane, 1,3-dichlorotetraisopropyldisiloxane, 1,1,3,3-tetraisopropyl-1,3-dichlorodisiloxane, 1,3-dichloro-1,1,3,3-tetraisopropyl-disiloxane, disiloxane, 1,3-dichloro-1,1,3,3-tetrakis 1-methylethyl, 1,1,3,3-tetraisopropyl-1,3-dichlorosiloxane, chloro chlorodiisopropylsilyl oxy diisopropylsilane, chloro-chloro-di propan-2-yl silyl oxy-di propan-2-yl silane, tipdsicl2, tipdsi-cl2
PubChem CID 172404
IUPAC Name chloro-[chloro-di(propan-2-yl)silyl]oxy-di(propan-2-yl)silane
SMILES CC(C)[Si](C(C)C)(O[Si](C(C)C)(C(C)C)Cl)Cl

Specifications

Boiling Point 69°C to 70°C (0.5mmHg)
Quantity 25 g
UN Number UN1760
Beilstein 1934216
Flash Point >110°C (230°F)
Solubility Information Miscible with dimethylformamide,hexane,ethyl acetate,chloroform and dichloromethane.
Formula Weight 315.43
Percent Purity 97%
Refractive Index 1.454
Sensitivity Moisture sensitive
Density 0.986
Chemical Name or Material 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane
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Safety and Handling

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Product Identifier
  • 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane
 Signal Word
  • Danger
 Hazard Category
  • Serious eye damage/eye irritation Category 1
  • Skin corrosion/irritation Category 1 B
 Hazard Statement
  • H314-Causes severe skin burns and eye damage.
  • H318-Causes serious eye damage.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.
 Supplemental information
  • MIXTURE LIST-Contain: 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane
SDS

RUO – Research Use Only

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