CAS RN 953769-46-5

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Sotuletinib, MedChemExpress

MedChemExpress Sotuletinib (BLZ945) is a potent, selective and brain-penetrant CSF-1R (c-Fms) inhibitor with an IC50 of 1 nM, showing more than 1,000-fold selectivity against its closest receptor tyrosine kinase homologs.

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Specifications

Molecular Weight (g/mol)	398.48
Color	Light Brown
Physical Form	Powder
Chemical Name or Material	Sotuletinib
Grade	Research
SMILES	O=C(C1=NC=CC(OC2=CC=C3N=C(N[C@H]4[C@H](O)CCCC4)SC3=C2)=C1)NC
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	95.0%
CAS	953769-46-5
Solubility Information	DMSO : 83.33 mg/mL (209.12 mM; Need ultrasonic)
Health Hazard 1	H302∣H315∣H319∣H335
Synonym	BLZ945
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₀H₂₂N₄O₃S
Formula Weight	398.48

CAS RN 953769-46-5

CAS RN 953769-46-5

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