CAS RN 946128-88-7

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Ro 5126766, MedChemExpress

MedChemExpress Ro 5126766 (CH5126766) is a first-in-class dual MEK/RAF inhibitor that allosterically inhibits BRAFV600E, CRAF, MEK, and BRAF (IC50: 8.2, 56, 160 nM, and 190 nM, respectively).

Pricing and Availability
Specifications

Molecular Weight (g/mol)	471.46
Color	Yellow
Physical Form	Solid
Chemical Name or Material	Ro 5126766
Grade	Research
SMILES	O=S(NC)(NC1=NC=CC(CC2=C(C)C3=CC=C(OC4=NC=CC=N4)C=C3OC2=O)=C1F)=O
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.08%
CAS	946128-88-7
Solubility Information	DMSO : 125 mg/mL (265.13 mM; Need ultrasonic)
Synonym	CH5126766
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₁H₁₈FN₅O₅S
Formula Weight	471.46

CAS RN 946128-88-7

CAS RN 946128-88-7

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