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Ro 5126766, MedChemExpress

Product Code. 16473577
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Product Code. Quantity unitSize
16473577 50 mg 50mg
16467558 10 mg 10mg
16467496 100 mg 100mg
16430038 5 mg 5mg
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Product Code. 16473577

Brand: Medchem Express HY18652

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Description

MedChemExpress Ro 5126766 (CH5126766) is a first-in-class dual MEK/RAF inhibitor that allosterically inhibits BRAFV600E, CRAF, MEK, and BRAF (IC50: 8.2, 56, 160 nM, and 190 nM, respectively).

Ro 5126766 (CH5126766) is a first-in-class dual MEK/RAF inhibitor that allosterically inhibits BRAFV600E, CRAF, MEK, and BRAF (IC50: 8.2, 56, 160 nM, and 190 nM, respectively).

Specifications

Chemical Name or Material Ro 5126766
CAS 946128-88-7
Color Yellow
Purity Grade Notes Research
Molecular Formula C21H18FN5O5S
Quantity 50 mg
Synonym CH5126766
Solubility Information DMSO : 125 mg/mL (265.13 mM; Need ultrasonic)
SMILES O=S(NC)(NC1=NC=CC(CC2=C(C)C3=CC=C(OC4=NC=CC=N4)C=C3OC2=O)=C1F)=O
Molecular Weight (g/mol) 471.46
Formula Weight 471.46
Percent Purity 98.08%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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