CAS RN 1603845-32-4

IUPAC Name: —

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Molecular Weight (g/mol): —

Molecular Formula: —

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Grade

Molecular Weight (g/mol)

Percent Purity

Physical Form

Quantity

MedChemExpress TX1-85-1 is an irreversible Her3 (ErbB3) inhibitor with an IC50 of 23 nM. TX1-85-1 is also the first selective Her3 ligand, which forms a covalent bond with Cys721 located in the ATP-binding site of Her3. TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	580.68
Color	White
Physical Form	Solid
Chemical Name or Material	TX1-85-1
Grade	Research
SMILES	CC(N1CCN(C2CCC(N3N=C(C4=CC(NC(C=C)=O)=C(OC5=CC=CC=C5)C=C4)C6=C3N=CN=C6N)CC2)CC1)=O
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.0%
CAS	1603845-32-4
Solubility Information	DMSO : 3.85 mg/mL (6.63 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	-20°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life	-20°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula	C₃₂H₃₆N₈O₃
Formula Weight	580.68

CAS RN 1603845-32-4

CAS RN 1603845-32-4

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