CAS RN 1513857-77-6

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Pemigatinib, MedChemExpress

MedChemExpress Pemigatinib (INCB054828) is an orally active, selective FGFR inhibitor with IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively. Pemigatinib has the potential for cholangiocarcinoma.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	487.5
Color	Yellow
Physical Form	Powder
Chemical Name or Material	Pemigatinib
Grade	Research
SMILES	CCN(C(N(C(C(F)=C(OC)C=C1OC)=C1F)C2)=O)C(C2=CN3)=C4C3=NC(CN5CCOCC5)=C4
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.84%
CAS	1513857-77-6
Solubility Information	DMSO : 25 mg/mL (51.28 mM; ultrasonic and warming and heat to 60°C)
Health Hazard 1	H302∣H315∣H319∣H335
Synonym	INCB054828
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₄H₂₇F₂N₅O₄
Formula Weight	487.5

CAS RN 1513857-77-6

CAS RN 1513857-77-6

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