CAS RN 1188910-76-0

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MedChemExpress Agerafenib (CEP-32496; RXDX-105) is a highly potent and orally efficacious inhibitor of BRAFV600E with a Kd of 14 nM.

Molecular Weight (g/mol)	517.46
Color	White
Physical Form	Solid
Chemical Name or Material	Agerafenib
Grade	Research
SMILES	O=C(NC1=NOC(C(C)(C)C(F)(F)F)=C1)NC2=CC=CC(OC3=C(C=C(OC)C(OC)=C4)C4=NC=N3)=C2
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	99.53%
CAS	1188910-76-0
Solubility Information	DMSO : 50 mg/mL (96.63 mM; Need ultrasonic)
Synonym	CEP-32496 RXDX-105
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₄H₂₂F₃N₅O₅
Formula Weight	517.46