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Description
ZCRB1 is a nuclear protein first identified in a differential display screen involving morphine-dependence-related genes. Its expression is increased following morphine treatment and has been observed to be elevated in HepG2 cells. ZCRB1 contains a CCHC-type zing finger RNA-binding motif and can interact with the DBA-binding domain of the stem cell regulator C/EBP transcription factors. ZCRB1 was identified as one of the protein components of U11/U12 snRNPs, which are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron, suggesting ZCRB1 may play a key role in U12-type splicing.
Specifications
Specifications
| Antigen | ZCRB1 |
| Applications | Immunocytochemistry, Immunofluorescence, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.37 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| Gene | ZCRB1 |
| Gene Accession No. | Q8TBF4, Q9CZ96 |
| Gene Alias | MADP 1, MADP1, RBM36, U11/U12 31K, U11/U12 snRNP 31 kDa protein, ZCCHC19, ZCRB1 |
| Gene Symbols | ZCRB1 |
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Product Title
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