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ZAP70 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 15592-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16884824

  • 3468.15 NOK / 150µL
Estimated Shipment: 22-12-2022
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Description

Description

Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3′ end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.
Specifications

Specifications

ZAP70
Polyclonal
Unconjugated
ZAP70
70 kDa zeta associated protein, SRK, STD, Syk related tyrosine kinase, Tyrosine protein kinase ZAP 70, TZK, ZAP 70, ZAP70
Rabbit
Antigen Affinity Chromatography
RUO
22637, 301348, 7535
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P43403, P43404
ZAP70
ZAP70 Fusion Protein Ag7943
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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