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  6. ZAP70 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

ZAP70 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. p-7207328 Shop All Proteintech Products
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20 μL
150 μL
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20µL
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Product Code. Quantity unitSize
16894824 20 μL 20µL
16884824 150 μL 150µL
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Product Code. 16894824 Supplier Proteintech Supplier No. 155921AP20UL

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Description

Rabbit Polyclonal Antibody

Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3′ end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation.

Specifications

Antigen ZAP70
Applications Immunoprecipitation, Immunofluorescence, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ZAP70
Gene Accession No. P43403, P43404
Gene Alias 70 kDa zeta associated protein, SRK, STD, Syk related tyrosine kinase, Tyrosine protein kinase ZAP 70, TZK, ZAP 70, ZAP70
Gene Symbols ZAP70
Host Species Rabbit
Immunogen ZAP70 Fusion Protein Ag7943
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22637, 301348, 7535
Target Species Human, Rat, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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