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Tocris Bioscience™ XL 184
GREENER_CHOICE

Potent VEGFR inhibitor; also inhibits other RTKs

Brand:  Tocris Bioscience™ 5422/50

Encompass

Product Code. 15776816

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Description

Description

XL 184 is a potent VEGFR inhibitor (IC50 = 0.035 nM); also inhibits c-Met, KIT, RET, FLT4, AXL, FLT3, FLT1 and Tie2 (IC50 values are 1.3, 4.6, 5.2, 6, 7, 11.3, 12 and 14.3 nM, respectively). Induces intratumoral hypoxia and apoptosis. Reduces tumor invasion and metastasis in vivo. Antiangiogenic.
Specifications

Specifications

>98%
Cabozantinib, BMS 907351
50 mg
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