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  6. Thermo Scientific Chemicals Wortmannin, Penicillium funiculosum, 99+%

Thermo Scientific Chemicals Wortmannin, Penicillium funiculosum, 99+%

Product Code. 15416129
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15416129 50 mg 50mg
15406129 25 mg 25mg
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Product Code. 15416129

Brand: Thermo Scientific Chemicals J63983.MF

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Description

Inhibitor of phosphatidylinositol 3-kinase | CAS: 19545-26-7 | C23H24O8, C23H24O8 | 428.44 g/mol

Wortmannin is used as inhibitor of phosphatidylinositol 3-kinase, used cell biology reagent that has been used previously in research to inhibit DNA repair, receptor-mediated endocytosis and cell proliferation. It inhibits fMLP induced PIP3 and superoxide anion production in guinea pig neutrophils. It blocks insulin metabolic effects in rat adipocytes without affecting the insulin receptor tyrosine kinase activity.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 19545-26-7
Molecular Formula C23H24O8, C23H24O8
Synonym KY 12420

Specifications

Quantity 50 mg
Description White to Off-white
Content And Storage -30°C to -10°C
For Use With (Application) Inhibitor of phosphatidylinositol 3-kinase
Formula Weight 428.44g/mol
Sensitivity Light Sensitive
Product Type Signal Transduction Reagent
Form Powder
Beilstein 67676
InChI Key QDLHCMPXEPAAMD-QAIWCSMKSA-N
SMILES COC[C@H]1OC(=O)C2=COC3=C2[C@@]1(C)C1=C([C@@H]2CCC(=O)[C@@]2(C)C[C@H]1OC(C)=O)C3=O
IUPAC Name (1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-6,11,16-trioxo-13,17-dioxapentacyclo[10.6.1.0²,¹⁰.0⁵,⁹.0¹⁵,¹⁹]nonadeca-2(10),12(19),14-trien-3-yl acetate
Molecular Weight (g/mol) 428.44
Assay ≥99%
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