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VU0357017 hydrochloride, MedChemExpress

Product Code. 16497696
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Product Code. 16497696 Supplier Medchem Express Supplier No. HY19752A

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Description

MedChemExpress VU0357017 hydrochloride (CID-25010775) is a potent, selective and brain-penetrant allosteric agonist of M1 muscarinic acetylcholine receptor, with an EC50 of 477 nM. VU0357017 hydrochloride is highly selective for M1 and has no activity at M2-M5 up to the highest concentrations tested (30 μM). VU0357017 hydrochloride can be used for the research of Alzheimer’s disease and schizophrenia.

VU0357017 hydrochloride (CID-25010775) is a potent, selective and brain-penetrant allosteric agonist of M1 muscarinic acetylcholine receptor, with an EC50 of 477 nM. VU0357017 hydrochloride is highly selective for M1 and has no activity at M2-M5 up to the highest concentrations tested (30 μM). VU0357017 hydrochloride can be used for the research of Alzheimer’s disease and schizophrenia.

Specifications

Chemical Name or Material VU0357017 hydrochloride
CAS 1135242-13-5
Color White
Purity Grade Notes Research
Molecular Formula C18H28ClN3O3
Quantity 100 mg
Synonym CID-25010775
Solubility Information H2O : 33.33 mg/mL (90.11 mM; Need ultrasonic) ∣DMSO : 25 mg/mL (67.59 mM; Need ultrasonic)
SMILES O=C(N1CCC(NCCNC(C2=CC=CC=C2C)=O)CC1)OCC.[H]Cl
Molecular Weight (g/mol) 369.89
Formula Weight 369.89
Percent Purity 99.28%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neuromodulation
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Research purposes only

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