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Voxtalisib, MedChemExpress

Product Code. 16496908
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Product Code. 16496908

Brand: Medchem Express HY15900

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Description

MedChemExpress Voxtalisib (XL765) is a potent PI3K inhibitor, which has a similar activity toward class I PI3K (IC50s=39, 113, 9 and 43 nM for p110α, p110β, p110γ and p110δ, respectively), also inhibits DNA-PK (IC50=150 nM) and mTOR (IC50=157 nM). Voxtalisib (XL765) inhibits mTORC1 and mTORC2 with IC50s of 160 and 910 nM, respectively.

Voxtalisib (XL765) is a potent PI3K inhibitor, which has a similar activity toward class I PI3K (IC50s=39, 113, 9 and 43 nM for p110α, p110β, p110γ and p110δ, respectively), also inhibits DNA-PK (IC50=150 nM) and mTOR (IC50=157 nM). Voxtalisib (XL765) inhibits mTORC1 and mTORC2 with IC50s of 160 and 910 nM, respectively.

Specifications

Chemical Name or Material Voxtalisib
Physical Form Solid
CAS 934493-76-2
Color Brown
Quantity 10 mg
Purity Grade Notes Research
Molecular Formula C13H14N6O
For Use With (Application) Cancer-Kinase/protease
Synonym XL765 SAR245409
Solubility Information DMSO : 10 mg/mL (37.00 mM; Need ultrasonic)
SMILES O=C1C(C2=NNC=C2)=CC3=C(C)N=C(N)N=C3N1CC
Molecular Weight (g/mol) 270.29
Formula Weight 270.29
Percent Purity 98.68%
Grade Research
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Research purposes only

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