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Description
Specifically deubiquitinates histone H2B at ′Lys-120′ (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons.
Specifications
Specifications
| Antigen | USP49 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.3 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | USP49 |
| Gene Accession No. | Q6P9L4, Q70CQ1 |
| Gene Alias | Deubiquitinating enzyme 49, Ubiquitin thiolesterase 49, USP49 |
| Gene Symbols | Usp49 |
| Show More |
Product Title
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