Learn More
Thermo Scientific Chemicals uPA Inhibitor II, UK122
Description
A cell-permeable oxazolidinone-carboxamidine compound that acts as a potent, selective, and active-site targeting inhibitor of urokinase-type plasminogen activatoruPA Inhibitor II, UK122 acts as a potent, selective and active-site targeting urokinase-type plasminogen activator (uPA) inhibitor. However, its activity against trypsin, thrombin, tPA, and plasmin is greatly reduced. It is also effectively inhibits the migration (80% inhibition) and invasion (68% inhibition) of uPA-expressing CFPAC-1 pancreatic cells, without affecting its proliferation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
- A cell-permeable oxazolidinone-carboxamidine compound that acts as a potent, selective, and active-site targeting inhibitor of urokinase-type plasminogen activator
Specifications
Specifications
| Quantity | 25 mg |
| Description | Yellow |
| Content And Storage | 2°C to 8°C |
| For Use With (Application) | A cell-permeable oxazolidinone-carboxamidine compound that acts as a potent, selective, and active-site targeting inhibitor of urokinase-type plasminogen activator |
| Molecular Formula | C17H13N3O2·CF3CO2H |
| Formula Weight | 405.30g/mol |
| Sensitivity | Light Sensitive |
| Product Type | Signal Transduction Reagent |
| Form | Solid |
RUO – Research Use Only
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.