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Invitrogen™ UBE2L3 Polyclonal Antibody

Description
Immunogen sequence: RKCGMKNFRN IQVDEANLLT WQGLIVPDNP PYDKGAFRIE INFPAEYPFK PPKITFKTKI YHPNIDEKGQ VCLPVISAEN WKPATKTDQV IQSLIALVND PQPEHPLRAD LAEEYSKDRK KFCKNAEEFT KKYGEKRPVD; Positive Samples: U-251MG, HL-60, K-562, HeLa, Mouse testis, Mouse brain, Mouse skeletal muscle; Cellular Location: Cytoplasm, Nucleus.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro.
Specifications
Specifications
| Antigen | UBE2L3 |
| Applications | ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1.27 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | UBE2L3 |
| Gene Accession No. | P68036, P68037 |
| Gene Alias | C79827; E2 ubiquitin-conjugating enzyme L3; E2-F1; L-UBC; UBCE7; UBCH7; UbcM4; Ube2l3; Ubiquitin carrier protein L3; ubiquitin conjugating enzyme E2 L3; ubiquitin conjugating enzyme E2L 3; ubiquitin-conjugating enzyme 7; ubiquitin-conjugating enzyme E2 L3; Ubiquitin-conjugating enzyme E2-F1; ubiquitin-conjugating enzyme E2L 3; ubiquitin-conjugating enzyme UBCH7; ubiquitin-protein ligase L3; Unknown (protein for MGC:127956) |
| Gene Symbols | UBE2L3 |
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