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UBE2E3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 15488-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16884684

  • 3468.15 NOK / 150µL
Estimated Shipment: 20-12-2022
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Description

Description

The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates.The first step requires the ATP-dependent activation of the Ub C-terminusand the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. A wide range of enzymes facilitate in the proteolytic Ub pathway including UBE2E3, also designated UBCH9, which catalyzes the covalent attachment of ubiquitin to other proteins and is involved in the regulation of transepithelial sodium transport in renal cells. UBE2E3 may also be involved in cell growth arrest. The UBE2E3 protein shuttles between the cytoplasm and nucleus in a IPO11-dependent manner. It is ubiquitously expressed at low levels and is highly expressed in skeletal muscle.
Specifications

Specifications

UBE2E3
Polyclonal
Unconjugated
UBE2E3
UBCE4, UBCH9, UbcM2, UBE2E3, Ubiquitin carrier protein E3, Ubiquitin protein ligase E3
Rabbit
Antigen Affinity Chromatography
RUO
10477, 22193, 295686
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin)
0.36 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P52483, Q969T4
UBE2E3
UBE2E3 Fusion Protein Ag7838
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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