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UAP1L1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 25262-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16893835

  • 3468.15 NOK / 150µL
Estimated Shipment: 22-12-2022
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Description

Description

UAP1 is a 56KDa isoform which catalyzes the final step of UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis from fructose-6-phosphate. UDP-GlcNAc, the activated form of GlcNAc moiety is used as a key precursor in N-linked glycosylation and the glycosylphosphatidylinositol (GPI)-anchor of cellular proteins. Crystallization studies revealed UAP1 is composed of a large central core flanked by two smaller extra domains. The central main domain displays a alpha/beta structure resembling the Rossmann fold. Northern Blot analysis detected abundant expression of UAP1 in testis and sperm with a low expression in placenta, muscle and liver. It is implicated in antibody-mediated infertility in males.
Specifications

Specifications

UAP1L1
Polyclonal
Unconjugated
UAP1L1
UAP1L1
Rabbit
Antigen Affinity Chromatography
RUO
91373
-20°C
Liquid
Western Blot, Immunofluorescence, Immunocytochemistry
0.43 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q3KQV9
UAP1L1
Peptide
150 μL
Primary
Human
Antibody
IgG
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