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UAP1L1 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 25262-1-AP-20UL
Additional Details : Weight : 0.00010kg
Description
UAP1 is a 56KDa isoform which catalyzes the final step of UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis from fructose-6-phosphate. UDP-GlcNAc, the activated form of GlcNAc moiety is used as a key precursor in N-linked glycosylation and the glycosylphosphatidylinositol (GPI)-anchor of cellular proteins. Crystallization studies revealed UAP1 is composed of a large central core flanked by two smaller extra domains. The central main domain displays a alpha/beta structure resembling the Rossmann fold. Northern Blot analysis detected abundant expression of UAP1 in testis and sperm with a low expression in placenta, muscle and liver. It is implicated in antibody-mediated infertility in males.Specifications
UAP1L1 | |
Polyclonal | |
Unconjugated | |
UAP1L1 | |
UAP1L1 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
91373 | |
-20°C | |
Liquid |
Immunofluorescence, Western Blot, Immunocytochemistry | |
0.43 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
Q3KQV9 | |
UAP1L1 | |
Peptide | |
20 μL | |
Primary | |
Human | |
Antibody | |
IgG |