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Trimethyl orthoformate, 99%
Description
Trimethyl orthoformate is used as a protecting group for aldehydes in organic synthesis, as an additive in polyurethane coatings and as a dehydrating agent in the preparation of surface modified colloidal silica nanoparticles. It is also used as a chemical intermediate in the preparation of vitamin B1 and sulfa drugs. It acts as an effective solvent for thallium(III) nitrate-mediated oxidations. Furthermore. It is utilized for the synthesis of chromone from keto-hydroxy naphthol in the presence of trimethylamine.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Trimethyl orthoformate is used as a protecting group for aldehydes in organic synthesis, as an additive in polyurethane coatings and as a dehydrating agent in the preparation of surface modified colloidal silica nanoparticles. It is also used as a chemical intermediate in the preparation of vitamin B1 and sulfa drugs. It acts as an effective solvent for thallium(III) nitrate-mediated oxidations. Furthermore. It is utilized for the synthesis of chromone from keto-hydroxy naphthol in the presence of trimethylamine.
Solubility
Miscible with ether, alcohol and benzene.
Notes
Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with acids and strong oxidizing agents.
Specifications
Specifications
| Melting Point | -53°C |
| Density | 0.968 |
| Boiling Point | 101°C to 102°C |
| Flash Point | 15°C (59°F) |
| Refractive Index | 1.379 |
| Quantity | 100 mL |
| UN Number | UN3272 |
| Beilstein | 969215 |
| Sensitivity | Moisture sensitive |
| Merck Index | 14,6884 |
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Safety and Handling
- Trimethyl orthoformate
- Danger
- Serious eye damage/eye irritation Category 2
- Flammable liquid Category 2
- H225-Highly flammable liquid and vapour.
- H319-Causes serious eye irritation.
- P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
- P240-Ground/bond container and receiving equipment.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- MIXTURE LIST-Contains : Trimethyl orthoformate
RUO – Research Use Only
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