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TRADD Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 15468-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16894654

  • 1611.84 NOK / 20µL
Estimated Shipment: 08-03-2024
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Description

Description

TRADD′s nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A. Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
Specifications

Specifications

TRADD
Polyclonal
Unconjugated
TRADD
Hs.89862, TRADD
Rabbit
Antigen Affinity Chromatography
RUO
71609, 8717
-20°C
Liquid
Immunoprecipitation, Western Blot
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q15628, Q3U0V2
Tradd
TRADD Fusion Protein Ag7768
20 μL
Primary
Mouse, Human
Antibody
IgG
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