missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. Aminobenzoic acids and derivatives
  8. Tolfenamic acid, 99+%

Tolfenamic acid, 99+%

Product Code. 15473869
Change view
Click to view available options
Quantity:
5 g
10 g
Unit Size:
10g
5g
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity Unit Size
15473869 10 g 10g
15463869 5 g 5g
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Product Code. 15473869 Supplier Thermo Scientific Alfa Aesar Supplier No. J61256.09
 Restricted Item
In Stock
Add to basket

missing translation for 'validMainframeMsg'

This item is not returnable. View return policy

Description

NSAID that activates calcium-activated potassium channels | CAS: 13710-19-5 | C14H12ClNO2 | 261.705 g/mol

Tolfenamic acid is a non-steroidal anti-inflammatory agent. It interferes with synthesis of β-amyloid precursor protein, and thus Aβ peptides, by promoting degradation of an essential transcription factor. It inhibits fMLP- and A23187-induced Ca2+ influx in human PMNL with an IC50 value of approximately 20 μM.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Tolfenamic acid is a non-steroidal anti-inflammatory agent. It interferes with synthesis of β-amyloid precursor protein, and thus Aβ peptides, by promoting degradation of an essential transcription factor. It inhibits fMLP- and A23187-induced Ca2+ influx in human PMNL with an IC50 value of approximately 20 µM.

Solubility
Soluble in water (slightly), acetone (∼10 mg/ml), DMSO (52 mg/ml at 25°C), methanol (∼10 mg/ml) and ethanol (50 mg/ml).

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 13710-19-5
Molecular Formula C14H12ClNO2
Molecular Weight (g/mol) 261.705
MDL Number MFCD00133865
InChI Key YEZNLOUZAIOMLT-UHFFFAOYSA-N
Synonym tolfenamic acid, clotam, n-3-chloro-2-methylphenyl anthranilic acid, 2-3-chloro-2-methylphenyl amino benzoic acid, tolfedine, acido tolfenamico, acide tolfenamique, acidum tolfenamicum, tolfine, n-2-methyl-3-chlorophenyl anthranilic acid
PubChem CID 610479
ChEBI CHEBI:32243
IUPAC Name 2-(3-chloro-2-methylanilino)benzoic acid
SMILES CC1=C(C=CC=C1Cl)NC2=CC=CC=C2C(=O)O

Specifications

Color White
Quantity 10 g
UN Number UN2811
Merck Index 14,9513
Solubility Information Soluble in water (slightly),acetone (∽10mg/ml),DMSO (52mg/ml at 25°C),methanol (∽10mg/ml) and ethanol (50mg/ml).
Formula Weight 261.7
Percent Purity ≥99%
Physical Form Crystalline Powder
Chemical Name or Material Tolfenamic acid

Safety and Handling

compliance-icons
Product Identifier
  • Tolfenamic acid
 Signal Word
  • Danger
 Hazard Category
  • Acute toxicity Category 3
 Hazard Statement
  • H301-Toxic if swallowed.
 Precautionary Statement
  • P264-Wash face, hands and anyexposed skin thoroughly after handling.
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
Supplemental information
  • MIXTURE LIST-Contain: Tolfenamic acid
SDS

RUO – Research Use Only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.