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TNPO2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 17831-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16887824

  • 3468.15 NOK / 150µL
Estimated Shipment: 22-12-2022
to see stock.

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Description

Description

Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
Specifications

Specifications

TNPO2
Polyclonal
Unconjugated
TNPO2
IPO3, Karyopherin beta 2b, KPNB2B, TNPO2, transportin 2, TRN2
Rabbit
Antigen Affinity Chromatography
RUO
212999, 30000, 304670
-20°C
Liquid
Western Blot, Immunofluorescence, Immunocytochemistry
0.4 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O14787, Q99LG2
Tnpo2
TNPO2 Fusion Protein Ag12229
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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