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TNFSF9 Mouse anti-Human, Clone: 1B4B1, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 66450-1-IG-150UL
Additional Details : Weight : 0.00010kg
Description
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.Specifications
TNFSF9 | |
Monoclonal | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
P41273 | |
TNFSF9 | |
TNFSF9 Fusion Protein Ag12768 | |
150 μL | |
Primary | |
Human | |
Antibody | |
IgG1 |
Western Blot | |
1B4B1 | |
Unconjugated | |
TNFSF9 | |
4 1BB L, 4 1BB ligand, 4 1BBL, CD137L, TNFSF9 | |
Mouse | |
Protein G | |
RUO | |
8744 | |
-20°C | |
Liquid |