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TNFSF9 Mouse anti-Human, Clone: 1B4B1, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66450-1-IG-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16888335

  • 3468.15 NOK / 150µL
Estimated Shipment: 20-12-2022
to see stock.

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Description

Description

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.
Specifications

Specifications

TNFSF9
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P41273
TNFSF9
TNFSF9 Fusion Protein Ag12768
150 μL
Primary
Human
Antibody
IgG1
Western Blot
1B4B1
Unconjugated
TNFSF9
4 1BB L, 4 1BB ligand, 4 1BBL, CD137L, TNFSF9
Mouse
Protein G
RUO
8744
-20°C
Liquid
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