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Timapiprant sodium, MedChemExpress

Product Code. 16452567
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Quantity:
5 mg
10 mg
50 mg
Unit Size:
10mg
50mg
5mg
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Product Code. 16452567

Brand: Medchem Express HY15342A

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Description

MedChemExpress Timapiprant sodium (OC000459 sodium) is a potent, selective, and orally active D prostanoid receptor 2 (DP2, also known as CRTH2) antagonist. Timapiprant sodium (OC000459 sodium) potently displaces [3H] PGD2 from human recombinant DP2 (Ki=13 nM), rat recombinant DP2 (Ki=3 nM), and human native DP2 (Ki=4 nM). Timapiprant sodium (OC000459 sodium) inhibits mast cell activation of Th2 lymphocytes and eosinophils.

Timapiprant sodium (OC000459 sodium) is a potent, selective, and orally active D prostanoid receptor 2 (DP2, also known as CRTH2) antagonist. Timapiprant sodium (OC000459 sodium) potently displaces [3H] PGD2 from human recombinant DP2 (Ki=13 nM), rat recombinant DP2 (Ki=3 nM), and human native DP2 (Ki=4 nM). Timapiprant sodium (OC000459 sodium) inhibits mast cell activation of Th2 lymphocytes and eosinophils.

Specifications

Chemical Name or Material Timapiprant sodium
CAS 950688-14-9
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C21H16FN2NaO2
Quantity 50 mg
Synonym OC000459 sodium
Solubility Information DMSO : 100 mg/mL (270.01 mM; Need ultrasonic)
SMILES O=C(O[Na])CN1C2=CC=C(F)C=C2C(CC3=NC4=C(C=CC=C4)C=C3)=C1C
Molecular Weight (g/mol) 370.35
Formula Weight 370.35
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neuromodulation
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Research purposes only

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