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TIM3 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 4C4G3, Proteintech
Mouse Monoclonal Antibody
1611.84 NOK - 4593.76 NOK
Specifications
Antigen | TIM3 |
---|---|
Clone | 4C4G3 |
Concentration | 1 mg/mL |
Applications | Immunohistochemistry (Paraffin), Western Blot |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16807485
|
Proteintech
60355-1-IG-20UL |
20 μL |
1611.84 NOK
20µL |
Estimated Shipment: 14-05-2024 Log in to see stock. |
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16897475
|
Proteintech
60355-1-IG-150UL |
150 μL |
4593.76 NOK
150µL |
Estimated Shipment: 14-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
TIM3 is a 280 aa membrane protein with a calculated molecular weight of 33 kDa, the higher molecular weights between 50 and 70 kDa detected by this monoclonal antibody probably represent glycosylated TIM3.
TIM3 (Hepatitis A virus cellular receptor 2, HAVCR2, T-cell immunoglobulin, mucin-dmain containing-3) is a 281 amino acid long, Type-1 Th1- specific cell surface glycoprotein expressed on terminally differentiated CD4+Th1 and CD8+Tc1 cells. TIM3 consists of an IgV-like domain, a mucin-like domain in the extracellular region, and a conserved Tyrosine phosphorylation motif in the cytoplasmic region. TIM3 is involved in macrophage activation and induction of autoimmune diseases. Further, TIM3 down-regulates aggressive Th1-mediated immune responses and facilitates in the development of immune tolerance. Pathological significance of TIM3 has been attributed to Experimental autoimmune encephalomyelitis (EAE), a Th-1 dependent autoimmune disease, and also enhances the severity of experimental autoimmune encephalomyelitis in mice.Specifications
TIM3 | |
1 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
CD366, HAVcr 2, HAVCR2, KIM 3, T cell membrane protein 3, Tim 3, TIM3, TIM-3, TIMD 3, TIMD3 | |
Havcr2 | |
IgG1 | |
Protein G | |
Antibody |
4C4G3 | |
Immunohistochemistry (Paraffin), Western Blot | |
Unconjugated | |
Mouse | |
Human, Mouse, Porcine, Rat | |
P0C0K5, Q8TDQ0, Q8VIM0 | |
100522045, 171285, 363578, 84868 | |
TIM3 Fusion Protein Ag16901 | |
Primary | |
-20°C | |
HAVCR2 |