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TIAF1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 20328-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16889844

  • 3468.15 NOK / 150µL
Estimated Shipment: 22-12-2022
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Description

Description

TIAF-1 (TGFB1-induced anti-apoptotic factor 1), also known as MYO18A, is a TGFB1-induced anti-apoptotic factor that functions to inhibit the cytotoxic effects of TNF-alpha, TRADD and FADD. It localizes to the nucleus and significantly up-regulated in activated helper T lymphocytes (TH2) in chronic kidney and liver allograft rejection. Suppression of TIAF1 expression by siRNA prevents UV irradiation-mediated p53 phosphorylation and nuclear translocation. TIAF1 is essential in the p53- and WOX1-mediated cell death and shows an aggregation-dependent control of tumor progression and metastasis, and regulation of cell death.
Specifications

Specifications

TIAF1
Polyclonal
Unconjugated
TIAF1
MAJN, MYO18A, MYSPDZ, SPR210, TIAF1
Rabbit
Antigen Affinity Chromatography
RUO
9220
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
0.18 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O95411
TIAF1
TIAF1 Fusion Protein Ag14023
150 μL
Primary
Human
Antibody
IgG
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