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Thermo Scientific™ TheraPure 2ʹ-OMe-Ac-C Phosphoramidite

Product Code. 17957152 Shop All Thermo Scientific Products
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Quantity:
1 g
Format:
Amber Bottle (20-400 Thread)
Serum Vial Bottle
Unit Size:
1g
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Product Code. Quantity Format Unit Size
17957152 1 g Amber Bottle (20-400 Thread) 1g
17997152 1 g Serum Vial Bottle 1g
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Product Code. 17957152 Supplier Thermo Scientific™ Supplier No. 27204310
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Description

2'-OMe-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-O-methyl protection, for use in oligonucleotide synthesis.

2'-OMe-C CEP is a phosphoramidite containing 5' DMT and the nucleoside cytidine (C) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in an amber bottle.

Available with a Serum Vial, 20-400 Finish, or 28-400 Finish neck style.

  • Serum vial neck style is compatible with most Applied Biosystems synthesizers and AKTA synthesizers.
  • 20-400 finish neck style is compatible with most Expedite synthesizers.
  • 28-400 finish neck style is compatible with most MerMade synthesizers.

Features:

  • Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-O-methyl-cytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
  • Molecular formula—C42H52N5O9P
  • Base—C
  • Base Protection—Ac
  • Formula weight—801.86 g/mol
  • CAS number—199593-09-4
  • HPLC purity—≥99%; M-11 Impurity: ≤0.01%; Single critical impurity ≤0.3%
  • 31P NMR purity—>99%; Sum of non-primary peaks at 140-152 ppm ≤0.5%
TRUSTED_SUSTAINABILITY

Spécification

Format Amber Bottle (20-400 Thread)
For Use With (Equipment) Expedite Synthesizers
Product Type 2in-OMe-C CEP
Content And Storage Store in freezer (at or below -20°C).
Nucleoside Type Cytidine (C)
Reagent Features 2in-OMe modified
Shipping Condition Room Temperature
Purity 99%
Quantity 1 g
Reagent Type Phosphoramidite
Grade TheraPure™
Nucleic Acid Type RNA
Product Line TheraPure
Form Powder
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For Research Use Only.

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