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Description
THEM2, also known as ACOT13, belongs to the hotdog-fold superfamily and possesses thioesterase activity, with greater activity observed with longer chain acyl-CoAs such as myristoyl- and palmitoyl-CoA. THEM2 is highly expressed in several tissues such as heart, kidney, liver and brain and has been shown to be co-localized with beta-tubulin on microtubules. THEM2 interacts with StarD, a protein that plays a key role in fatty acid metabolism, and the addition of StarD to THEM2 increased its catalytic activity, suggesting that THEM2 plays a significant role in the metabolism of fatty acids. At least two isoforms of THEM2 are known to exist.
Specifications
Specifications
| Antigen | THEM2 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunofluorescence |
| Classification | Polyclonal |
| Concentration | 0.17 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | ACOT13 |
| Gene Accession No. | Q9CQR4, Q9NPJ3 |
| Gene Alias | ACOT13, Acyl CoA thioesterase 13, HT012, PNAS 27, THEM2 |
| Gene Symbols | Acot13 |
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Product Title
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