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TGR5 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA523182

Additional Details : Weight : 0.01000kg

Product Code. 13287738

  • 4090.00 NOK / 100µL
Estimated Shipment: 06-06-2024
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Description

Description

This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.
Specifications

Specifications

TGR5
Polyclonal
Unconjugated
GPBAR1
BG37; C16DUPq36.3; DUP7q36.3; G protein-coupled bile acid receptor 1; G protein-coupled receptor; G protein-coupled receptor TGR5; Gpbar1; GPCR; GPCR HBG37; GPCR19; GPR131; G-protein coupled bile acid receptor 1; G-protein coupled bile acid receptor BG37; G-protein coupled receptor GPCR19; hBG37; Helodermin-preferring VIP receptor; hGPCR19; M-BAR; membrane bile acid receptor; membrane-type receptor for bile acids; PACAP type III receptor; PACAP-R3; PACAP-R-3; pituitary adenylate cyclase-activating polypeptide type III receptor; Tgr5; vasoactive intestinal peptide receptor 2; vasoactive intestinal polypeptide receptor 2; vasopressive intestinal peptide receptor 2; VIP and PACAP receptor 2; VIP receptor subtype 2; Vip2; VIP2R; VIPR2; VIP-R-2; VPAC2; VPAC2 receptor; VPAC2R; VPCAP2R
Rabbit
Affinity chromatography
RUO
151306, 227289, 338443
-20° C, Avoid Freeze/Thaw Cycles
Liquid
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
1.0 mg/mL
PBS with 0.02% sodium azide
Q80SS6, Q80T02, Q8TDU6
GPBAR1
Synthetic peptide from C-terminus of the human TGR5/GPBAR1 protein [UniProt Q8TDU6]
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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