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TERF2IP Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1611.84 NOK - 4593.76 NOK

Specifications

Antigen TERF2IP
Concentration 0.19 mg/mL
Applications Immunohistochemistry (Paraffin), Immunocytochemistry, Immunoprecipitation, Flow Cytometry, Immunofluorescence
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16883304
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Proteintech
14595-1-AP-20UL
20 μL
1611.84 NOK
20µL
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Estimated Shipment: 17-04-2024
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16873304
View Documents Promotion Details
Proteintech
14595-1-AP-150UL
150 μL
4593.76 NOK
150µL
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Estimated Shipment: 17-04-2024
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Description

Description

Human Rap1 was the first identified ortholog of the yeast telomeric protein scRap1, which shares 3 conserved sequence motifs in common. HRap1 is located at telomeres and affects telomere length by being recruited to telomeres by TRF2 instead of directly binding to the telomere like scRap1. The hRap1 cDNA codes for a protein of 399 amino acids with approximate molecular weight of 47 kDa. The hRap1 protein does not interact with TRF1. TRF2 is a ubiquitously expressed protein that is implicated in the control of telomere length(1). TRF2, like TRF1 contains a Myb-related DNA binding motif. It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes. TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini. The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells. Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types.
Specifications

Specifications

TERF2IP
Immunohistochemistry (Paraffin), Immunocytochemistry, Immunoprecipitation, Flow Cytometry, Immunofluorescence
Unconjugated
Rabbit
Rat, Human, Mouse
Q5EAN7, Q91VL8, Q9NYB0
307861, 54386, 57321
TERF2IP Fusion Protein Ag6130
Primary
-20°C
TERF2IP
0.19 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
DRIP5, hRap1, RAP1, RAP1 homolog, TERF2IP
Terf2ip
IgG
Antigen Affinity Chromatography
Antibody
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SDS
Documents

Documents

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