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  6. Tenovin-6, MedChemExpress

Tenovin-6, MedChemExpress

Product Code. 16466786
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Product Code. 16466786 Supplier Medchem Express Supplier No. HY15510

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Description

MedChemExpress Tenovin-6, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity. Tenovin-6 inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC50s of 21 μM, 10 μM, and 67 μM, respectively. Tenovin-6 also inhibits dihydroorotate dehydrogenase (DHODH).

Tenovin-6, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity. Tenovin-6 inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC50s of 21 μM, 10 μM, and 67 μM, respectively. Tenovin-6 also inhibits dihydroorotate dehydrogenase (DHODH).

Specifications

Chemical Name or Material Tenovin-6
Physical Form Solid
CAS 1011557-82-6
Color Yellow
Quantity 100 mg
Purity Grade Notes Research
Molecular Formula C25H34N4O2S
For Use With (Application) Cancer-programmed cell death
Solubility Information DMSO : ≥ 31 mg/mL (68.19 mM)
SMILES O=C(NC(NC1=CC=C(NC(CCCCN(C)C)=O)C=C1)=S)C2=CC=C(C(C)(C)C)C=C2
Molecular Weight (g/mol) 454.63
Formula Weight 454.63
Percent Purity 98.67%
Grade Research
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Research purposes only

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