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Invitrogen™ TDE1 Polyclonal Antibody
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Product Code. 15769461 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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15769461 100 μL 100µL
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Product Code. 15769461 Supplier Invitrogen™ Supplier No. PA561654

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EMETYLKKIP GFCEGGFKIH EADINADKDC DVLVGYK Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 65%.

TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue. It is believed TDE1 contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis. The mechanism through which TDE1 protects cells is poorly understood, but may involve aberrant methylation of TDE1 complexes.
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Specifications

Antigen TDE1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Serinc3
Gene Accession No. Q13530
Gene Alias AA959945; AA960047; Aigp1; AIGP-1; axotomy-induced glyco/Golgi protein 1; Axotomy-induced glycoprotein 1; DIFF33; Membrane protein TMS-1; SBBI99; Serinc3; Serine incorporator 3; TDE; TDE1; Tms1; TMS-1; tumor differentially expressed 1; tumor differentially expressed protein 1
Gene Symbols Serinc3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TDE1. Recombinant protein control fragment (Product #RP-99433).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10955
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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