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MedChemExpress Tat-NR2B9c TFA

Product Code. 16403986
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25 mg
Unit Size:
25mg
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16403986 25 mg 25mg
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Product Code. 16403986 Supplier MedChemExpress Supplier No. HYP0117A

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Description

MedChemExpress Tat-NR2B9c TFA (Tat-NR2Bct TFA) is a postsynaptic density-95 (PSD-95) inhibitor, with EC50 values of 6.7 nM and 670 nM for PSD-95d2 (PSD-95 PDZ domain 2) and PSD-95d1, respectively.

Tat-NR2B9c TFA disrupts the PSD-95/NMDAR interaction, inhibiting NR2A and NR2B binding to PSD-95 with IC50 values of 0.5 μM and 8 μM, respectively. Tat-NR2B9c TFA also inhibits neuronal nitric oxide synthase (nNOS)/PSD-95 interaction, and possesses neuroprotective efficacy.

Specifications

Purity 98.99%
CAS 1834571-04-8
Content And Storage Protect from light, stored under nitrogen∣Powder -80°C 2 years, -20°C 1 year∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light, stored under nitrogen)
For Use With (Application) Neuroscience-Neurodegeneration
Molecular Weight (g/mol) 2632.9 g/mol
Product Type Peptides
Quantity 25 mg
Shipping Condition Room temperature
Solubility H2O : ≥ 50 mg/mL (18.99 mM)
Synonym Tat-NR2Bct TFA∣NA-1 TFA
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