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Tacrolimus, MedChemExpress

Product Code. 16495838
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Product Code. 16495838

Brand: Medchem Express HY13756

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Description

MedChemExpress Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties.

Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties.

Specifications

Chemical Name or Material Tacrolimus
CAS 104987-11-3
Color White
Purity Grade Notes Research
Molecular Formula C44H69NO12
Quantity 10 mg
Synonym FK506 Fujimycin FR900506
Solubility Information DMSO : ≥ 150 mg/mL (186.56 mM)
SMILES O=C([C@@](CCCC1)([H])N1C(C([C@@]2(O)[C@H](C)C[C@H](OC)[C@@](O2)([H])[C@@H](OC)C[C@@H](C)C/C(C)=C/[C@H]3CC=C)=O)=O)O[C@H](/C(C)=C/[C@H]4C[C@@H](OC)[C@H](O)CC4)[C@H](C)[C@@H](O)CC3=O
Molecular Weight (g/mol) 804.02
Formula Weight 804.02
Percent Purity 95.2%
Grade Research
Physical Form Powder
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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