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TOKU-E™ Streptomycin ReadyMade™ Solution

Product Code. 30044034
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10 x 1 mL
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Product Code. 30044034 Supplier TOKU-E™ Supplier No. S13910x1ML

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Description

Streptomycin ReadyMade™ Solution is provided as a sterile-filtered solution of Streptomycin Sulfate in water.

  • CAS Number: 3810-74-0
  • Molecular Formula: C21H39N7O12 · 1.5 H2SO4
  • Molecular Weight: 728.69 g/mol
  • Storage Conditions: -20°C
  • Form: Liquid
  • Source: Streptomyces griseus
  • Spectrum: Streptomycin Sulfate is highly active against Gram-negative and mycobacterium, and less active against Gram-positive bacteria. Streptomycin Sulfate has been found to be effective against certain β-lactam sensitive vancomycin-resistant Enterococcus (VRE) species; a glycopeptide antibiotic resistant 'superbug'. It is also active against mycobacteria
  • Mechanism of Action: Streptomycin is a protein synthesis inhibitor. It binds to the small 16S rRNA of the 30S subunit of the bacterial ribosome, interfering with the binding of formyl-methionyl-tRNA to the 30S subunit. This leads to codon misreading, eventual inhibition of protein synthesis and ultimately death of microbial cells through mechanisms that are still not understood. Speculation on this mechanism indicates that the binding of the molecule to the 30S subunit interferes with 50S subunit association with the mRNA strand. This results in an unstable ribosomal-mRNA complex, leading to a frameshift mutation and defective protein synthesis and eventually to cell death

Specifications

Chemical Name or Material Streptomycin Sulfate
Physical Form Liquid
CAS 3810-74-0
Source Streptomyces griseus
Packaging 2 mL plastic vial
Sterile Filtered Yes, 0.22 μm
Sterility Sterile
Color Colorless
Concentration 100 to 105 mg/mL
Quantity 10 x 1 mL
Purity Grade Notes >90% (HPLC)
Assay Percent Range 650 to 850 μg/mg
Assay Percent Notes Streptomycin Sulfate, Dried Basis
Molecular Formula (C21H39N7O12)2 · 3 H2SO4
Product Line ReadyMade™ Solutions
Shipping Condition Ice Pack
Synonym Streptomycin sulphate, Streptomycin sesquisulfate
IUPAC Name 2-[(1R,2R,3S,4R,5R,6S)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine;sulfuric acid
Molecular Weight (g/mol) 1457.41 g/mol
Formula Weight 1457.41 amu
Percent Purity >90%
Grade Antibiotic
Concentration or Composition (by Analyte or Components) Streptomycin Sulfate ≥10%
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