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Description
STIP1 is an adaptor protein that coordinates the functions of HSP70 and HSP90 in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 ).
Specifications
Specifications
| Antigen | STIP1 |
| Applications | Western Blot, Immunofluorescence, Immunoprecipitation, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.13 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | STIP1 |
| Gene Accession No. | O35814, P31948, Q60864 |
| Gene Alias | HOP, Hsc70/Hsp90 organizing protein, IEF SSP 3521, P60, STI1, STI1L, STIP1 |
| Gene Symbols | Stip1 |
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Product Title
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