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STAT5B Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 12071-1-AP-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16889563

  • 3468.15 NOK / 150µL
Estimated Shipment: 22-12-2022
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Description

Description

This antibody is a rabbit polyclonal antibody raised against residues near the N terminus of human STAT5B.

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
Specifications

Specifications

STAT5B
Polyclonal
Unconjugated
STAT5B
STAT5, STAT5B
Rabbit
Antigen Affinity Chromatography
RUO
20851, 25126, 6777
-20°C
Liquid
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence, Immunocytochemistry
0.14 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P42232, P51692, P52632
STAT5B
STAT5B Fusion Protein Ag2709
150 μL
Primary
Rat, Mouse, Human
Antibody
IgG
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