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SPDP, MedChemExpress
Description
SPDP (SPDP Crosslinker) is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. It is a glutathione cleavable ADC linker used for the antibody-drug conjugates (ADCs).
Specifications
Specifications
| Chemical Name or Material | SPDP |
| CAS | 68181-17-9 |
| Color | White |
| Purity Grade Notes | Research |
| Molecular Formula | C12H12N2O4S2 |
| Quantity | 500 mg |
| Synonym | SPDP Crosslinker |
| Solubility Information | DMSO : 155 mg/mL (496.22 mM; Need ultrasonic) |
| SMILES | O=C(ON1C(CCC1=O)=O)CCSSC2=NC=CC=C2 |
| Molecular Weight (g/mol) | 312.36 |
| Show More |
Research purposes only
Product Title
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