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  6. SPAG5 Rabbit anti-Human, Polyclonal, Proteintech

SPAG5 Rabbit anti-Human, Polyclonal, Proteintech

Product Code. p-7206274 Shop All Proteintech Products
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Quantity:
150 μL
20 μL
Unit Size:
150µL
20µL
Product Code. Quantity unitSize
16883514 20 μL 20µL
16873514 150 μL 150µL
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Product Code. 16883514

Brand: Proteintech 147261AP20UL

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Description

Rabbit Polyclonal Antibody

This antibody is specific to SPAG5.

SPAG5 (sperm associated antigen 5), also known as MAP126, hMAP126, DEEPEST or Astrin, is a 1,193 amino acid protein that is expressed at high levels in testis and at lower levels in liver, placenta, pancreas, colon and thymus. Localized specifically to spindle poles during prophase and throughout the spindle during metaphase and anaphase, SPAG5 is essential for proper spindle formation and is thought to be involved in the dynamic and functional regulation of mitotic spindles. Additionally, SPAG5 plays a role in sister chromatid cohesion and subsequent chromatid separation and, via its association with chromatids, is an important regulator of chromosome integrity. SPAG5 has a long stalk and a globular head domain through which if forms a homodimer that is characterized by aster-like structures. Upon DNA damage, SPAG5 may be phosphorylated by ATR or ATM.

Specifications

Antigen SPAG5
Applications Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence, Immunocytochemistry, Immunoprecipitation
Classification Polyclonal
Concentration 0.36 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SPAG5
Gene Accession No. Q96R06
Gene Alias Astrin, DEEPEST, hMAP126, MAP126, SPAG5, sperm associated antigen 5
Gene Symbols SPAG5
Host Species Rabbit
Immunogen SPAG5 Fusion Protein Ag6485
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10615
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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