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Sotuletinib, MedChemExpress

Product Code. p-200098296
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Product Code. Quantity unitSize
16488047 5 mg 5mg
16425976 100 mg 100mg
16421537 50 mg 50mg
16415338 10 mg 10mg
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Product Code. 16488047

Brand: Medchem Express HY12768

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Description

MedChemExpress Sotuletinib (BLZ945) is a potent, selective and brain-penetrant CSF-1R (c-Fms) inhibitor with an IC50 of 1 nM, showing more than 1,000-fold selectivity against its closest receptor tyrosine kinase homologs.

Sotuletinib (BLZ945) is a potent, selective and brain-penetrant CSF-1R (c-Fms) inhibitor with an IC50 of 1 nM, showing more than 1,000-fold selectivity against its closest receptor tyrosine kinase homologs.

Specifications

Chemical Name or Material Sotuletinib
CAS 953769-46-5
Color Light Brown
Purity Grade Notes Research
Molecular Formula C20H22N4O3S
Quantity 5 mg
Synonym BLZ945
Solubility Information DMSO : 83.33 mg/mL (209.12 mM; Need ultrasonic)
SMILES O=C(C1=NC=CC(OC2=CC=C3N=C(N[C@H]4[C@H](O)CCCC4)SC3=C2)=C1)NC
Molecular Weight (g/mol) 398.48
Formula Weight 398.48
Percent Purity 95.0%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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