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Invitrogen™ SNAP25 Polyclonal Antibody
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Product Code. 11558571
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Product Code. 11558571 Supplier Invitrogen™ Supplier No. PA1740

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Description

Rabbit Polyclonal Antibody

PA1-740 detects synaptosomal associated protein 25 (SNAP-25) from bovine, mouse, rat and zebra fish (Danio rerio) samples. PA1-740 has been successfully used in Western blot and immunofluorescence procedures. By Western blot, this antibody detects a 25 kDa protein representing SNAP-25 in whole rat brain, mouse brain and zebra fish extracts. Immunofluorescence staining of SNAP-25 in cultured rat hippocampal cells with PA1-740 yields a pattern consistent with cytoplasmic and plasma membrane staining. PA1-740 immunizing peptide corresponds to the C-terminal amino acid residues 195-206 of mouse SNAP-25. This sequence is completely conserved between mouse, rat, human, chicken, and goldfish. PA1-740 immunizing peptide (Cat. # PEP-032) is available for use in neutralization and control experiments.

SNAP25 is a t-SNARE involved in the molecular regulation of neurotransmitter release. It may play a role in the synaptic function of specific neuronal systems. SNAP25 associates with proteins involved in vesicle docking and membrane fusion. It also regulates plasma membrane recycling through its interaction with CENPF. Mutations in the gene can results in myasthenic syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SNAP25
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Snap25
Gene Accession No. P60879, P60881, Q17QQ3, Q5TZ66
Gene Alias ALMS1; bA416N4.2; Bdr; blind drunk; CG17676; CG17884; CG40452; CMS18; dJ1068F16.2; Dmel CG40452; Dmel_CG40452; etID17571.20; etID69167.20; fj42b02; fj45g04; fj48c02; FLJ23079; GENA70; HGNC:11132; resistance to inhibitors of cholinesterase 4 homolog; RIC4; RIC-4; SEC9; si:dkeyp-8f4.6; Snap; SNAP 25; snap25; SNAP-25; snap25.1; SNAP-25.1; snap25a; SNAP-25A; SNAP-25B; snp25; sp; SUP; super protein; synaptosomal associated protein-25; synaptosomal-associated 25 kDa protein; Synaptosomal-associated protein 25; synaptosomal-associated protein 25-A; synaptosomal-associated protein, 25 kDa; synaptosomal-associated protein, 25a; synaptosomal-associated protein, 25kDa; synaptosome associated protein 25; synaptosome associated protein 25a; synaptosome associated protein 25kDa; synaptosome-associated protein 25.1; synaptosome-associated protein 25a; wu:fj42b02; wu:fj45g04; wu:fj48c02
Gene Symbols Snap25, snap25a
Host Species Rabbit
Immunogen Synthetic Peptide:(C)- A(195) N Q R A T K M L G S G(206).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20614, 25012, 30712, 540853
Target Species Mouse, Rat, Bovine, Zebrafish
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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